Cortical Connections 2015
- 19-20th March 2015
Queensland Brain Institute,
The University of Queensland
- Variable rates for registration
For the human brain to work, it must be wired correctly during development. How this occurs is one of the fundamental questions of neuroscience.
This conference brings together international leaders in normal and abnormal wiring of the cerebral cortex and cognitive function. A special focus will be the development and cognitive function of the corpus callosum and the genetic basis of how callosal malformations arise, their diagnosis, and their impact on cognition.
The corpus callosum is the largest fibre tract in the mammalian brain. It is an evolutionary innovation only found in placental mammals. It has important functions in human behaviour, sensory and motor function and language. Corpus callosum malformations occur in isolation or as part of over 64 different human congenital syndromes. Symptoms include sensory and motor deficits, language and learning difficulties, and most commonly problems with social interactions.
This meeting will provide clinical neurologists, neurosurgeons, geneticists, psychiatrists and psychologists with up-to-date information on corpus callosum function and malformations, as well as the clinical management of patients. Sessions include development, genetics, imaging and cognitive function of cortical wiring.
Participants are encouraged to submit abstracts and present posters at the meeting. A subset of abstracts will be selected for short talks in each session.
- Vicki Anderson, Murdoch Children’s Research Institute, Melbourne
- Tania Attié-Bitach, Hospital Necker-Enfants Malades & Université Paris Descartes, Paris
- Tianzi Jiang, Queensland Brain Institute, Brisbane
- Roberto Lent, Federal University of Rio de Janeiro
- Richard Leventer, Murdoch Children’s Research Institute, Melbourne
- Paul Lockhart, Murdoch Children’s Research Institute, Melbourne
- George McGillivray, Murdoch Children’s Research Institute, Melbourne
- Fernanda Tovar-Moll, Federal University of Rio de Janeiro and D’Or Institute for Research and Education
- Kathryn North, Murdoch Children’s Research Institute, Melbourne
- Lynn Paul, Caltech, Los Angeles
- Gail Robinson, The University of Queensland, Brisbane
- Elliott Sherr, University of California San Francisco
- Stephen Williams, Queensland Brain Institute, Brisbane
Session 1: Development of Cortical Wiring
The development of circuits in the brain is crucial to function. This session will cover the cellular and molecular mechanisms required to form cortical circuits and the electrophysiological properties of cortical circuits. An overview of human cortical malformations that affect cortical wiring, including agenesis of the corpus callosum, will also be discussed.
Session 2: Genetics of Cortical Wiring Disorders
Advances in human genetics are occurring rapidly. This session will cover the latest research on identifying the causative genes of human cortical wiring disorders. Speakers will present their research using genome sequencing, single nucleotide polymorphism analysis, copy number variation, insertion and deletion analyses, mutational analysis and epigenetic regulation of gene function.
Session 3: Imaging Cortical Wiring
Neuroimaging provides a mechanism for diagnosing and potentially sub-phenotyping disorders of cortical wiring. Research using multimodal magnetic resonance imaging (T1, diffusion and functional MRI) will be highlighted as well as the computational analysis of this data in mapping cortical wiring and overall brain connectivity. Recent data demonstrating the plasticity of human cortical wiring and the development of ectopic projections in some individuals will also be discussed.
Session 4: Cognitive function and Cortical Wiring Disorders
The output of cortical wiring is the cognitive function of the brain. This session will focus on the function of the human corpus callosum and how these functions are altered in disorders of cortical wiring. The cognitive diagnosis and treatment of these individuals will also be discussed by experts in the field.
Please include title, author, affiliation, a brief description of your research and an acknowledgment of funding sources. Max 250 words.
Email firstname.lastname@example.org by Friday 27 February